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In a phase II study of the long-acting GLP-1RA efpeglenatide (4 mg once weekly, 6 mg once weekly, 6 mg once every 2 weeks, and 8 mg once every 2 weeks), patients with obesity and without diabetes had statistically significant reductions in body weight compared with placebo after 20 weeks of treatment (differences in least squares means were 6.3 to 7.2 kg
Care 2, 97101
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High-fat meals delay gastric emptying independently of cagrilintide, so dosing before a high-fat dinner can compound the effect and increase nausea risk
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