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So by extension, weight loss with GLP-1s does result in loss of muscle as well as loss of fat
From a medical perspective, the main goal of treatment is to improve cardiometabolic control
Tirzepatide Side Effects# Well-characterized from Phase 3 (SURPASS, SURMOUNT) trials and post-market surveillance: Gastrointestinal : Nausea (12-33%), diarrhea (12-21%), vomiting (5-12%), constipation (6-11%) Decreased appetite : Common and expected pharmacological effect Injection site reactions : Mild, occurring in 2-5% of patients Pancreatitis : Rare
Conclusion: We identified and validated Itfg1 as a target for enhancing the endogenous regenerative capacity of the liver
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