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But retatrutide may be even more effective , for several reasons: Glucagon receptor activation promotes hepatic fat oxidation Reduces liver fat accumulation more robustly Improves liver enzyme levels (ALT, AST) In a subgroup analysis of the retatrutide Phase 2 trial: Patients with suspected NAFLD showed a 70%+ reduction in liver fat content , measured by MRI-PDFF These effects surpassed the reductions seen with tirzepatide and semaglutide in comparable studies Another study showed that 93% of patients on the highest dose of retatrutide had 100% resolution of fatty liver
These results already have been published in the American Journal of Clinical Nutrition
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A third section was used to stain acid-producing parietal cells of the corpus of the stomach by using an antibody directed against the H + K + ATPase -subunit (Abcam, Cambridge, UK
