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They showed that semaglutide enhanced histological parameters of fibrosis and inflammation while decreasing hepatic expression of genes associated with fibrotic and inflammatory cascade: through proteomic profiling of serum from MASH patients treated with semaglutide, they detected 72 proteins linked to disease resolution and validated these findings in preclinical mouse models and an independent patient cohort [28]
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Obesity in Adults: Drug Therapy. Edited by F Xavier Pi-Sunyer and Sara Swenson, UpToDate, Wolters Kluwer, 21 Dec
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