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IGF-1 Lr3 (Insulin-like Growth Factor-I Long R3) is an 83 amino acid analog of human IGF-I comprising the complete human IGF-I sequence with the substitution of an Arg for the Glu at position 3 (hence R3), as well as a 13 amino acid extension peptide at the N-terminus
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Synergistic mechanism between the endoplasmic reticulum and mitochondria and their crosstalk with other organelles
Noteworthy, these two membrane transporters are also responsible for drug uptake in the cell, further highlighting their role in developing novel anti-cancer approaches and/or improving those already existing
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