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The clinical data from ESSENCE showed that at week 72, 36.8% of people treated with Wegovy achieved improvement in liver fibrosis with no worsening of steatohepatitis compared to 22.4% treated with placebo
Explicit Prescribing Information Guidance The prescribing information for branded medications containing semaglutide (like Wegovy) and tirzepatide (like Zepbound) explicitly advises against co-administration with other GLP-1 receptor agonists or tirzepatide-containing products
Wegovy is FDA approved for chronic weight management in adults with obesity and overweight with at least one weight-related condition, such as high blood pressure, type 2 diabetes, or high cholesterol
Given the positive results seen, some studies have recommended that thyroid hormone replacement therapy always be considered prior to surgical intervention
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