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This was largely driven by reductions in risk of ischaemic stroke (RR 0.73) and the composite of ischaemic stroke or TIA (RR 0.76)
For context, the Mounjaro FDA prescribing information lists injection-site reactions among the documented adverse events across the SURPASS trials at roughly 3-7% uncommon but consistent enough that a methodical approach matters from day one
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0.07) was less than prespecified noninferiority margin of 0.4%
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