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Starting GLP-1 medications prematurely can cause increased nausea and vomiting, delayed gastric emptying, compromised nutritional intake, dehydration, and potentially delayed wound healing
Cellular control over lipid peroxidation is achieved by modulating PUFA substrate availability through mechanisms encompassing -oxidation, phospholipid remodeling, and lipid storage
Using SGLT inhibitors and incretin-based approaches Incretin-based therapies and sodium-glucose cotransporter 2 (SGLT-2) inhibitors are now being worked on as novel classes of glucose-lowering drugs used in the management of T2DM and are proving to be playing a simultaneous role in improving liver health (224) (Table 3)
Microdosing refers to starting at the lowest therapeutic dose and increasing gradually over weeks or months, rather than jumping to standard clinical doses immediately
