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Metformin is a biguanide that primarily reduces hepatic glucose production and improves insulin sensitivity in peripheral tissues without causing hypoglycaemia
This maintenance study proved intriguing following an exploratory arm (Figure 4) of the VENTURE Oral trial that titrated patients rapidly to 90mg for six weeks before dropping to a 30mg maintenance dose
Formularies typically have three to five tiers, and each plan decides which drugs fall into which tiers based on negotiations with drug companies and other cost factors
Understanding these effects will help you better manage your treatment and talk with your doctor about any concerns
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