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In the Phase 2 obesity data the weight curve was still trending downward at 48 weeks, so a genuine plateau at a tolerated maintenance dose may simply reflect the body settling toward a new set point rather than the protocol failing
Campbell, J
These are women, primarily, who have reported back to us that [using GLP-1s] wasnt worth the weight loss. Eli Lillys recent retatrutide clinical trial did not evaluate participants changes in muscle or bone mass, a company spokesperson tells Scientific American
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