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Lower fat: Fat slows gastric emptying, and many people find lower-fat preparations more comfortable while adjusting to a GLP-1 medication

Potential Side Effects Although both peptides are well-tolerated, some patients may experience: Mild water retention Joint stiffness (temporary) Insulin sensitivity changes (rare) Injection site irritation Patients should always be monitored by a physician trained in peptide therapy, and adjustments can be made to dose or frequency to mitigate any issues

According to FDA prescribing information, Rybelsus should be used as part of a comprehensive diabetes management program

Dietary modificationsincluding smaller, more frequent meals and reduced fat intakecan help manage both postcholecystectomy symptoms and medication-related gastrointestinal effects