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Increasing evidence indicates that dysregulated crotonylation contributes to tumor initiation, progression, metastasis, and therapy resistance across diverse cancer types
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The 2023 phase 2 double-blind, randomized controlled trial evaluating a GLP-1/GIP/glucagon receptor triagonist (retatrutide) in patients with the disease of obesity reported 24.2% weight loss at 48 weeks with 12 mg retatrutide
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