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Nearly 20 agents and extracts, including iron chelators and transporter, antioxidants, pharmacodynamic element from traditional Chinese medicine (TCM), ferroptosis-related protein inhibitors, and neuroprotective agent that inhibit ferroptosis have been reported to have a remissioning effect on retinal disease in animal models (Table 2
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This disulfide/thiol switch is operated by cytosolic Grx2 as modulator/terminator (Brutigam et al., 2011
J., Orskov, C., Nielsen, O
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