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While older treatments (like Ozempic) mimic only one hormone, Mounjaro mimics two: GLP-1 and GIP

In humans, the CYP450 enzyme that predominately catalyses the formation of NAPQI is CYP2E1, although in vitro CYP3A4, CYP2D6 and CYP1A2 have also been implicated in the formation of the toxic metabolite [18,19,20]

Esta terapia no se recomienda para mujeres embarazadas o en perodo de lactancia