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Discontinuation Rates: The Real Tolerability Test The number that matters most for tolerability is the discontinuation rate
With respect to the wider GLP-1 drug class, the UK SmPCs for semaglutide (available on the electronic Medicines Compendium, emc) and tirzepatide (Mounjaro SmPC, emc) document GI adverse effects including nausea, vomiting, diarrhoea, constipation, and dyspepsia as well-characterised class effects
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We will look at whether increasing your levels can help manage the irritation associated with acid reflux and why the way you take this supplement matters more than you might think
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