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These drugs can lead to substantial weight loss, especially with tirzepatide, but the likely result is far from uniform, and response may depend on factors medicine still does not fully understand

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Chromatin immunoprecipitation in RNaseH1-depleted U-2 OS cells further demonstrated recruitment of SFPQ to diverse classes of repetitive elements, including telomeric repeats, subtelomeres of Chr16p, Sat III, Sat II, centromeric -satellite repeats, AluS, AluY, and LINE elements (Fig

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