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Patients with genetic variants affecting GLP-1 receptor signaling or glucose metabolism may also benefit from providers experienced in interpreting biomarker context during dose optimization

As the pharmacological action and impact on CV parameters interpreted from the CV outcomes trials seemingly differed between both classes of glucose-lowering agents, they should be used accordingly, that is, after taking into consideration a patients needs and drug tolerability

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It is about restoring capacity, rebuilding strength, improving mechanics, and safely returning to activity