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[11] Tirzepatide is a prescription medication approved by the FDA for the treatment of type 2 diabetes (under the brand name Mounjaro) and chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity (under the brand name Zepbound)
It enhances insulin secretion from pancreatic -cells in a glucose-dependent manner, whilst simultaneously suppressing glucagon release from -cells ( Notably, GLP-1 appears to be a key messenger of the gut-brain axis
Altered dietary salt intake for preventing diabetic kidney disease and its progression
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