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Stimulant laxatives like senna and bisacodyl should be used sparingly and only under provider guidance, as they actively trigger intestinal contractions that could theoretically amplify GLP-1's gastric effects
However, extreme fatigue, especially when accompanied by other symptoms like severe dizziness, confusion, or jaundice, should be evaluated by a healthcare provider
You have already been making lifestyle changes, including a reduced-calorie diet, for at least three months prior to starting Zepbound
Mansur A et al
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