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Abnormal adipocytes that undergo phenotypic changes under the influence of tumor cells are referred to as cancer-associated adipocytes (CAAs), which exhibit microscopic characteristics such as smaller cell volume and LDs, fibroblast-like changes, and reduced lipid differentiation [128] due to an increase in mitochondrial FAO
TME-mediated cancer resistance and combating strategies The TME in cancer resistance The TME constitutes a critical layer of therapeutic resistance in which immune and stromal cells, extracellular matrix remodeling, and vascularmetabolic constraints jointly restrict drug and immune efficacy (Fig
Environ., 33, 173182, 1999
In an industry where innovation cycles move rapidly and consumer trends evolve quickly, this level of research capacity allows a manufacturer to stay ahead of emerging ingredient technologies and formulation concepts
