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In vitro BBB models have revealed the role of BBB adhesion molecules, including ICAM-1, E-selectin, and PECAM-1, in transmigration of monocytes (Sguin et al., 2003), dendritic cells (Sagar et al., 2012), neutrophils (Wong et al., 2007), and lymphocytes (Wong et al., 1999)
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Always check the expiration date before using, and discard the vial if the solution appears discolored or contains particles
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