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Extensive research has found that it achieves this by stimulating collagen production, improving skin elasticity while minimizing the appearance of fine lines and wrinkles in mature skin

That being said, I dont know, anybody have any tales, any anecdotal, any thoughts, or just even where they want to see this go

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A 2019 ultrasound study (Gibney et al., Diabetes Obesity and Metabolism ) measured actual needle-tip placement in 240 subcutaneous injections and found that the "always 45 degrees" rule produced correct placement in only 64% of injections