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We previously tested whether linagliptin reduces pathophysiologic abnormalities in diastolic and vascular endothelial dysfunction in two translationally relevant rodent models of obesity and insulin resistance, the Zucker Obese (ZO) rat [34] and the WD-fed mouse [35, 42]
The better response is almost boring
Mild side effects like soreness at the injection site or temporary digestive changes may occur, but serious reactions are rare
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