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Peminda Cabandugama, MD, an endocrinologist and obesity medicine specialist at Cleveland Clinic in Ohio, found the results to be slightly surprising. The pharmacokinetics [how drugs move through the body] of GLP-1 medications show a half-life of 5 days, which means the current standard of using these medications every 7 days is also stretching this out, says Dr

Effects include reduced inflammatory markers in synovial fluid, preserved cartilage thickness on imaging, improved joint function scoring

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These medications can cause low blood sugar when combined with GLP-1 drugs