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FDA-approved transdermal drug patches (such as nicotine patches or hormone patches) have demonstrated effectiveness for their intended purposes
The pathophysiological mechanisms of CIPN are complex, involving multiple interconnected processes including oxidative stress, neuroinflammation, neurotrophic factor depletion, and mitochondrial dysfunction
General Dosage: 1.6 to 1.9 kilos inject 0.3 cc IM 2.0 to 2.3 kilos inject 0.4 cc IM
A unified head-to-head pharmacology comparison in a standardized assay system would be needed to confirm these rankings
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