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CJC-1295 and Ipamorelin are generally well-tolerated, and Ipamorelin's selectivity (minimal effect on cortisol and prolactin) is part of why this combo is favored
Therefore, do not exceed a total daily dose of 8 mg in patients with severe hepatic impairment (Child-Pugh score of 10 or greater) [see Dosage and Administration (2.2), Clinical Pharmacology (12.3)]
If constipation persists despite these measures, healthcare providers may consider temporarily delaying dose increases or reducing the tirzepatide dose
Use an alcohol swab to disinfect the rubber top of the vial and dispose of the swab properly
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