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rat or mouse, the disease subtype of Diabetes mellitus (DM), the number of animals in this study utilized as the control group and the experimental or the DCM group, the dose, route of administration and the number of consecutive days the STZ was injected, the blood sugar cutoff point which confirms that diabetes was induced, the gender, age and bodyweight of the rodent species, and the primary outcomes reported by each included study are described in this table (Table 4)

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Their effectiveness depends on treatment consistency, severity of pigmentation, and proper skincare practices such as sun protection

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