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Its difficult to distinguish direct anti-inflammatory effects from the benefits of weight loss and improved metabolic health, but the pattern is consistent enough to warrant further study. A 2025 study found that RA patients with a BMI over 27 taking GLP-1 medications showed improvements in symptoms and disease activity
Tong, K.I., et al., Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response
Pyroptosis, a pro-inflammatory programmed cell death triggered by activated Caspase-1/Caspase-11, which can lead to inflammatory cytokines IL-18/IL-1 release to activate pro-inflammatory immune cell mediators
A European health authority, however, announced that it couldnt find any link in humans
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