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Semaglutide may influence the metabolism of SSRIs through the cytochrome P450 enzyme system via the CYP2C19 and CYP2D6 subtypes

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However, this same mechanism creates an environment where: Food undergoes prolonged exposure to gastric acid and digestive enzymes Gas production, including potentially hydrogen sulfide, can accumulate Gastric distension may trigger nausea, bloating, and belching Additionally, Ozempic affects intestinal motility throughout the gastrointestinal tract

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