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While injection-site irritation is well recognized, clinicians are increasingly observing broader skin changes in patients treated with semaglutide (Ozempic, Wegovy), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro, Zepbound)
Currently enrolled in phase 2 clinical trials, MariTide is expected to conclude by late 2024, with future studies in phase 3 focusing on obesity and its associated conditions, including heart, liver, and kidney diseases
Dose escalation protocols used in trials were designed to minimise gastrointestinal tolerability issues
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