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By antagonizing the mu-opioid receptor, naltrexone prevents beta-endorphins from inhibiting POMC neurons, thus promoting the release of -MSH and enhancing the anorexigenic pathway
[1] Adequate hydration should be emphasised
Cultural narratives about willpower, personal responsibility, and moral failure in obesity create receptivity to messages that frame medication as cheating, addiction, or dangerous shortcuts
People who take Wegovy may be at an increased risk of these vision problems
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