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doi:10.3390/ijms222413662 Zhou L, Jang KY, Moon YJ, et al

This reduction causes an increase in falls, fractures and physical disability, reduced function, loss of quality of life and increased mortality [1, 2]

Likewise, several other chemotherapeutic agents, such as platinum complexes (e.g., cisplatin) [194] and sorafenib [195], enhance mitochondrial ROS production or hinder the antioxidant system, thereby causing heightened ROS levels within cancer cells