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The isoform 1 protein is composed of 662 amino acids and the isoform 2 protein is composed of 629 amino acids
L., Sarkar, S., Garg, N.,
Piche T, des Varannes SB, Sacher-Huvelin S, Holst JJ, Cuber JC, Galmiche JP
In the next sections, we will briefly introduce thiazides, thiazide-like and loop diuretics from a historic perspective to illustrate how the success of one specific class of these diuretics in treating hypertension overshadowed their undesired metabolic effects and reduced our curiosity to study them to better understand their basic and clinical pharmacology
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