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Metabolomic profiling revealed an obvious increase in oligopeptides containing branched-chain amino acids (BCAAs) in AILI mice, whereas these metabolites were significantly negatively correlated with the abundance of BSL, but positively with key genes of Hippo pathway

These NFB-regulated inflammatory factors accelerate islet -cell apoptosis, cause insulin resistance in peripheral cells, and play an essential role in the pathogenesis of diabetes (123)

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Ghasemi, V., Kheirkhah, M., Neisani Samani, L., & Vahedi, M