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J Diet Suppl 2022

Carcinogenesis, Mutagenesis, Impairment of Fertility

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Although semaglutide had clearly been reported in clinical trials for increasing the risk of acute pancreatitis and pancreatic cancer, as well as promoting levels of lipase and amylase, several meta-analyses had revealed contrary results ( Semaglutide-related pancreatitis was more likely to be reported as a severe AE with strong clinical priority, arousing our great interest to further explore its detailed characteristics