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This is believed to be linked to the increased metabolic efficiency of the prefrontal cortex, the "CEO" of the brain, which often begins to decline in efficiency as GH levels drop with age (somatopause)
10.3390/ph14100979 Pharmaceuticals
This accumulation dampens IFNB1-mediated signaling, reducing activation of downstream transcription factors signal transducer and activator of transcription 1 (STAT1), STAT2, and IFN-stimulated genes
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