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Clinical Status Human RCT | Observational | Animal | In vitro Primarily studied in preclinical and regional aging research contexts, with limited exploratory human data

The portal blood contains toxic materials absorbed in the intestine, and therefore the liver is the first tissue to be exposed to toxic substances that have been absorbed through the gastro-intestinal tract

Tesamorelin gained FDA approval in 2010 for reducing visceral adipose tissue, with clinical trials demonstrating 1518% reductions in visceral fat after 26 weeks at 2mg daily dosing