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Appropriate protective equipment such as gloves, lab coats, and safety glasses should always be worn when handling the substance

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This process is particularly pronounced when glutathione (GSH) is depleted or glutathione peroxidase 4 (GPX4), a key enzyme that prevents lipid oxidation, is inhibited [39]

Notably, PEG-coated CeO 2 NPs retain their superoxide dismutase (SOD)-like and catalase (CAT)-like enzyme mimetic activities, although multi-PEG coatings slightly reduce CAT-like activity by approximately 20% ( However, the influence of surface coatings on the bioactivity of CeO 2 NPs, especially regarding their intrinsic redox activity, requires careful consideration