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Prata et al., 2020
GHK-Cu (glycyl-L-histidyl-L-lysine copper) is a naturally occurring tripeptide bound to a copper ion
Plasma concentrations measure around 200 ng/mL at age 20 and drop to roughly 80 ng/mL by age 60 a decline of more than 60%
The clinical translation of these trial results, which will be important for the comparison of GLP-1RAs with SGLT2 inhibitors in the treatment of patients with heart failure and a preserved ejection fraction, remains to be determined
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