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Abstract Background The insulin/IGF-1 signaling pathway has a major role in the regulation of longevity both in Caenorhabditis elegans and mammalian species, i.e., reduced activity of this pathway extends lifespan, whereas increased activity accelerates the aging process

Tirzepatide vs semaglutide and liraglutide for weight loss in patients with overweight or obesity without diabetes: a short-term cost-effectiveness analysis in the United States

In many cases the medication can be continued with appropriate precautions, rather than automatically held

Impact on appetite GLP-1RAs act on GLP-1 receptors located in the brainstem and the hypothalamus, which is often referred to as the brain's appetite control center