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Rifampicin reduced the bioluminescence of intracellular bacteria, consistent with its ability to penetrate mammalian cell membranes and inhibit bacterial transcription, thereby reducing metabolic activity (Fig
This crucial phase of the malady, in analogy with other viral infections and to a widely accepted pharmacological praxis, should be timely treated either with etiotropic drugs (which in COVID-19 case are still lacking) as well as with host-directed agents to manage/prevent the symptoms (Kaufmann et al., 2018)
However, glutathione has been linked to a decrease in these types of symptoms
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