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Levocarnitine, European Pharmacopoeia (ep) Reference Standard 138

For example, patients may benefit from eating more slowly, prioritizing lean proteins, reducing liquid calories, or spacing meals to avoid excessive hunger

Diarrhea and nausea were the most frequent adverse events

To overcome these limitations, this review discusses a range of structural modifications, including N-terminal and C-terminal substitutions, fatty acid conjugation, and large molecule fusion technologies, which have collectively contributed to enhanced half-life, increased stability, improved receptor affinity, and retained or augmented bioactivity of GLP-1 analogs