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Its intracellular depletion ultimately results in cell death, and its clinical relevance has been researched for decades

S2CID 4984228

The possible cytoprotective effects of the application of NaBPC157 were studied based on their effect on the initial Robert's model for a cytoprotective-agent screening of the ethanol-induced gastric lesions

On the basis of such standard assays, different isoforms are hereinafter referred to as enzymatically active or inactive glutaredoxins for the sake of simplicity (without excluding the possibility that inactive isoforms might actually catalyse other reactions with specialized substrates in vivo )