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[5] [6] Early-phase clinical trials including a Phase 2 trial published in the New England Journal of Medicine (2023) have reported significant reductions in body weight and improvements in metabolic markers, though this evidence remains preliminary and is not sufficient to establish a clinical dosing or reconstitution standard

Furthermore, aligned with the principles of culinary medicine (19), we included a paragraph aimed at integrating nutrition, medicine, and culinary arts while also addressing patients' frequent requests for nutritional counseling during oncologic treatment or follow-up

The therapeutic weight loss happens after the 5 mg escalation

Impact of gut Dysbiosis on Neurohormonal pathways in chronic kidney disease