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The tirzepatide safety profile appears favorable compared to some other GLP-1 medications, though patients with personal or family history of medullary thyroid carcinoma should not use tirzepatide or any GLP-1/GIP agonist
10.1016/j.ando.2022.04.004 205 VenkatesanA
Patients with a history of allergic reactions or sensitivities to GLP-1 receptor agonists, pancreatitis, thyroid cancerincluding medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN-2) generally are not suitable candidates for this therapy
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