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And the metabolic effects observed in the diabetes trials have opened a new research direction connecting IRR activation to metabolic health an area that intersects with the broader metabolic peptide landscape including compounds like retatrutide and MOTS-C that approach metabolic regulation through entirely different receptor systems
TB-500, on the other hand, has been linked to corneal wound research, where it appears to influence inflammatory signaling pathways and may reduce apoptosis in epithelial cells
10.1016/j.bbr.2020.112919 Summary Keywords retina, ischemia, BPC 157, L-NAME, rats Citation Zlatar M, Kokot A, Vuletic LB, Masnec S, Kralj T, Perisa MM, Barisic I, Radic B, Milanovic K, Drmic D, Seiwerth S and Sikiric P (2021) BPC 157 as a Therapy for Retinal Ischemia Induced by Retrobulbar Application of L-NAME in Rats
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