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Tip: The glucagon receptor component may cause slightly higher rates of nausea compared to semaglutide or tirzepatide at similar efficacy levels
PMID 10059978
Pericytes attach to the abluminal side of ECs and are responsible for vascular contraction and regulation of cerebral blood flow (Daneman and Prat, 2015
In a 32-week phase 2 trial investigating the effect of CagriSema on HbA1c in subjects with T2D and BMI 27 kg/m 2 , investigational drug is superior to cagrlintide 2.4 mg alone (-2.2% v -0.9%), but not compared to semaglutide 2.4 mg alone (-1.8%) (75)
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