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The nuclear factor-kappa B pathway and response to treatment in breast cancer
When beneficial gut bacteria ferment these fibers, they produce short-chain fatty acids (SCFAs), particularly butyrate
Animal As a senolytic, FOXO4-DRI carries mechanism-specific theoretical risks discussed in the senescence literature including disruption of beneficial senescence surveillance and off-target effects on stem-cell populations that share features with senescent cells and senolytic translation from mouse to human has a history of failures
PMID: 22 WangL
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