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Neuraminidase activity is present also in Streptococcus pneumoniae , and it has been proposed that this activity increases the adhesion to epithelial cells of meningococci containing sialic acid in their LOS and/or capsules (serogroup B, C, Y and W135) by degrading the surface-exposed sialic acid and unmasking the meningococcal adhesins (Shakhnovich et al., 2002)
Licensed access, side-effect management, and ongoing clinical review usually matter more than novelty
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Massive Investment, Long Road It is important to note that some GLP-1 agonist drugs require a 4-6 month titration period to reach the maximum dosage while avoiding severe side effects
