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Lastly, the wider CrIs in the NMA compared with the CI in SURMOUNT-5 may be explained by the use of a Bayesian analysis with random effect for the NMA, resulting in greater uncertainty in the results introduced by the heterogeneity of multiple trials per treatment comparison in the NMA
Control mice showed significant hepatic steatosis after 1 week of MCDD feeding, whereas mice with GSTM2 overexpression showed this effect at 4 weeks
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A physician legally permitted to prescribe may still reasonably decide this is not something their practice takes on
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